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Malondialydehyde ("MDA")
What is MDA?
BIOXYTECH® MDA-586
Spectrophotometric Assay for Malondialdehyde
For Research Use Only. Not For Use In Diagnostic Procedures.
Catalog Number 21044
Lipid peroxidation is a well-established mechanism of cellular injury in both plants
and animals, and is used as an indicator of oxidative stress in cells and
tissues. Lipid peroxides, derived from polyunsaturated fatty acids, are unstable and decompose
to form a complex series of compounds. These include reactive carbonyl compounds,
which is the most abundant malondialdehyde (MDA). Therefore,
measurement of malondialdehyde is widely used as an indicator of lipid peroxidation.
Increased levels of lipid peroxidation products have been associated
with a variety of chronic diseases in both humans and model systems. MDA reacts readily with amino groups
on proteins and other biomolecules to form a variety of adducts, including cross-linked products. MDA
also forms adducts with DNA bases that are mutagenic and possibly carcinogenic. DNA-protein cross-links are
another result of the reaction between DNA and MDA.
Free Radicals Test - colour chart
The above information is provided for general
educational purposes only. It is not intended to replace competent
health care advice received from a knowledgeable healthcare professional.
You are urged to seek healthcare advice for the treatment of any
illness or disease.
Health Canada and the FDA (USA) have not evaluated these
statements. This product is not intended to diagnose, treat, cure, or prevent
any disease.
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